The HOXB7 Antibody (CAB6925) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through rabbit immunization, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for studies utilizing Western blot techniques.HOXB7, a member of the HOX family of transcription factors, has been implicated in various biological processes, including embryonic development and cancer progression. Its dysregulation has been linked to tumorigenesis and metastasis in several cancer types, highlighting its potential as a therapeutic target for cancer treatment.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
HOXB7 Antibody
SKU:
CAB6925
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HOX2, HOX2C, HHO.C1, Hox-2.3, HOXB7
Positive Sample:
Mouse kidney
Cellular Localization:
Nucleus.
Calculated MW:
24kDa
Observed MW:
24kDa
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
Purification Method
Affinity purification
Gene ID
3217
RRID
AB_2767484
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse kidney, using HOXB7 Rabbit pAb (CAB6925) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
