Description
HPV31 E7 Recombinant Protein (C-His)
HPV31 E7 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu98, with a C-terminal His tag. Predicted molecular weight: 11.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. For research use only.
Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.
| Product Name: | HPV31 E7 Recombinant Protein (C-His) |
| SKU: | GXRP10138 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | HPV31 |
| Synonyms: | Protein E7, E7 |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu98 |
| Calculated MW: | 11.97 kDa |
| UniProt: | P17387 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
