Description
Human ABCC1 Recombinant Protein (N-His)
Human ABCC1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu848-Met967, with an N-terminal His tag. Predicted molecular weight: 15.61 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Multidrug resistance-associated protein 1 is a ~171 kDa protein. Mediates export of organic anions and drugs from the cytoplasm. For research use only.
Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation.
| Product Name: | Human ABCC1 Recombinant Protein (N-His) |
| SKU: | GXRP12455 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ABCC1, ATP-binding cassette sub-family C member 1, EC:7.6.2.2, EC:7.6.2.3, Glutathione-S-conjugate-translocating ATPase ABCC1, LTC4 transporter, Leukotriene C(4) transporter, MRP, MRP1, Multidrug resistance-associated protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu848-Met967 |
| Calculated MW: | 15.61 kDa |
| UniProt: | P33527 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
