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Human ABCC4 / MRP4 ELISA Kit

SKU:
HUFI00909
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O15439
Sensitivity:
0.938ng/ml
Range:
1.563-100ng/ml
ELISA Type:
Sandwich
Synonyms:
ABCC4, Multidrug resistance-associated protein 4, MRP4, MOAT-B, Multi-specific organic anion transporter B, ATP-binding cassette sub-family C member 4, MRP, cMOAT-related ABC transporter
Reactivity:
Human
Research Area:
Signal Transduction
€599
Frequently bought together:

Description

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Human ABCC4 / MRP4 ELISA Kit

ABCC4/MRP4 is a protein belonging to the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport a variety of molecules across both extra- and intra-cellular membranes. The vast majority of human ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCC4/MRP4 is part of the MRP subfamily and is involved in multi-drug resistance. The family member plays a detoxification role as a pump for its substrate, organic anions. It may also be involved in prostaglandin-induced cAMP signaling in ciliogenesis through alternative splicing. Dubin-Johnson Syndrome and Biliary Tract Disease are examples of diseases linked to ABCC4.