Description
Human ADAMTS1 Recombinant Protein (N-His)
Human ADAMTS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg258-Pro467, with an N-terminal His tag. Predicted molecular weight: 25.51 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) is a ~105 kDa protein. Metalloprotease which cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. For research use only.
Also cleaves COMP. Has angiogenic inhibitor activity. May play a critical role in follicular rupture. 1. de Groot, R. et al. (2025) Matrix biology : journal of the International Society for Matrix Biology 135, 106-124. PMID: 39672391 2. Vázquez, F. et al. (1999) The Journal of biological chemistry 274, 23349-57. PMID: 10438512
| Product Name: | Human ADAMTS1 Recombinant Protein (N-His) |
| SKU: | GXRP03029 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS1, METH1, METH-1, KIAA1346, ADAMTS-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg258-Pro467 |
| Calculated MW: | 25.51 kDa |
| UniProt: | Q9UHI8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
