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Human ADGRF1 Recombinant Protein (N-His)
Key Features

Human ADGRF1 Recombinant Protein (N-His) (GXRP11576)

SKU GXRP11576
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ADGRF1 Recombinant Protein (N-His)

Human ADGRF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr298-Pro575, with an N-terminal His tag. Predicted molecular weight: 32.95 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Adhesion G-protein coupled receptor F1 is a ~101 kDa protein. Adhesion G-protein coupled receptor (aGPCR) for N-docosahexaenoylethanolamine (synaptamide), an omega-3 fatty acid lipid highly enriched in the brain. For research use only.

Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRF1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple to G(q), G(i) and G(12)/G(13) G proteins; additional evidence is however required to confirm this result in vivo. Involved in the development of neurons and cognitive function.

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