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Human ADRA1A Recombinant Protein (N-His)
Key Features

Human ADRA1A Recombinant Protein (N-His) (GXRP01481)

SKU GXRP01481
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ADRA1A Recombinant Protein (N-His)

Human ADRA1A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser330-Val466, with an N-terminal His tag. Predicted molecular weight: 17.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Alpha-1A adrenergic receptor (ADRA1A) is a ~51 kDa protein. Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). For research use only.

Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C. ADRA1A binds the catecholamine ligands norepinephrine and epinephrine. Can also couple to G(14) protein. Nuclear ADRA1A forms heterooligomers with ADRA1B to regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

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