Description
Human AKAP8 Recombinant Protein (N-GST)
Human AKAP8 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Met1-Glu572, with an N-terminal GST tag. Predicted molecular weight: 91.06 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. A-kinase anchor protein 8 (AKAP8) is a ~76 kDa protein. Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). For research use only.
Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. May help to deliver cyclin D/E to CDK4 to facilitate cell cycle progression. Required for cell cycle G2/M transition and histone deacetylation during mitosis.
| Product Name: | Human AKAP8 Recombinant Protein (N-GST) |
| SKU: | GXRP06776 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | AKAP8, A-kinase anchor protein 8, AKAP95, AKAP-8, A-kinase anchor protein 95 kDa, AKAP 95 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Met1-Glu572 |
| Calculated MW: | 91.06 kDa |
| UniProt: | O43823 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
