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Human ALDOB Recombinant Protein (N-His)
Key Features

Human ALDOB Recombinant Protein (N-His) (GXRP00571)

SKU GXRP00571
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human ALDOB Recombinant Protein (N-His)

Human ALDOB Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr9-Tyr364, with an N-terminal His tag. Predicted molecular weight: 40.84 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fructose-bisphosphate aldolase B (ALDOB) is a ~39 kDa protein. Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. For research use only.

In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check.

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