Description
Human ANXA2 Recombinant Protein (N-His)
Human ANXA2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp339, with an N-terminal His tag. Predicted molecular weight: 40.77 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Annexin A2 (ANXA2) is a ~38 kDa protein. Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. For research use only.
It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. Binds to endosomes damaged by phagocytosis of particulate wear debris and participates in endosomal membrane stabilization, thereby limiting NLRP3 inflammasome activation.
| Product Name: | Human ANXA2 Recombinant Protein (N-His) |
| SKU: | GXRP00667 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Lipocortin II, Annexin A2, Calpactin-1 heavy chain, PAP-IV, p36, CAL1H, Calpactin I heavy chain, ANX2, ANX2L4, Protein I, Annexin-2, LPC2D, Annexin II, ANXA2, Placental anticoagulant protein IV, Chromobindin-8 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asp339 |
| Calculated MW: | 40.77 kDa |
| UniProt: | P07355 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
