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Human AP3B2 Recombinant Protein (N-His)
Key Features

Human AP3B2 Recombinant Protein (N-His) (GXRP02194)

SKU GXRP02194
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human AP3B2 Recombinant Protein (N-His)

Human AP3B2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly838-Gln1082, with an N-terminal His tag. Predicted molecular weight: 28.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. AP-3 complex subunit beta-2 (AP3B2) is a ~119 kDa protein. Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. For research use only.

The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

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