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Human APAF1 Recombinant Protein (N-His)
Key Features

Human APAF1 Recombinant Protein (N-His) (GXRP00079)

SKU GXRP00079
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human APAF1 Recombinant Protein (N-His)

Human APAF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser31-Phe350, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Apoptotic protease-activating factor 1 (APAF1) is a ~141 kDa protein. Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. For research use only.

This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

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