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Human APLP1 Recombinant Protein (N-His)
Key Features

Human APLP1 Recombinant Protein (N-His) (GXRP01756)

SKU GXRP01756
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human APLP1 Recombinant Protein (N-His)

Human APLP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg62-Phe202, with an N-terminal His tag. Predicted molecular weight: 18.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Amyloid beta precursor like protein 1 (APLP1) is a ~72 kDa protein. May play a role in postsynaptic function. For research use only.

The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

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