Description
Human ARHGEF5 Recombinant Protein (N-His)
Human ARHGEF5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser1136-Ala1597, with an N-terminal His tag. Predicted molecular weight: 55.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Rho guanine nucleotide exchange factor 5 is a ~176 kDa protein. Guanine nucleotide exchange factor which activates Rho GTPases. For research use only.
Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1. Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia.
| Product Name: | Human ARHGEF5 Recombinant Protein (N-His) |
| SKU: | GXRP10964 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ARHGEF5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, TIM, Transforming immortalized mammary oncogene, p60 TIM |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser1136-Ala1597 |
| Calculated MW: | 55.93 kDa |
| UniProt: | Q12774 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
