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Human ARPC2 Recombinant Protein (N-His)
Key Features

Human ARPC2 Recombinant Protein (N-His) (GXRP00104)

SKU GXRP00104
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human ARPC2 Recombinant Protein (N-His)

Human ARPC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg300, with an N-terminal His tag. Predicted molecular weight: 36.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Actin-related protein 2/3 complex subunit 2 (ARPC2) is a ~34 kDa protein. Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). For research use only.

The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).

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