Description
Human ATRAID Recombinant Protein (N-His)
Human ATRAID Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu31-Ser199, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. All-trans retinoic acid-induced differentiation factor is a ~24 kDa protein. Promotes osteoblast cell differentiation and terminal mineralization. For research use only.
Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol.
| Product Name: | Human ATRAID Recombinant Protein (N-His) |
| SKU: | GXRP13098 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | APR-3, APR3, ATRAID, All-trans retinoic acid-induced differentiation factor, Apoptosis-related protein 3, C2orf28, p18 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu31-Ser199 |
| UniProt: | Q6UW56 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
