Description
Human AURKC Recombinant Protein (N-His)
Human AURKC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu20-Gln277, with an N-terminal His tag. Predicted molecular weight: 32.32 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Aurora kinase C (AURKC) is a ~35 kDa protein. Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. For research use only.
The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Also plays a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'.
| Product Name: | Human AURKC Recombinant Protein (N-His) |
| SKU: | GXRP03090 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Serine/threonine-protein kinase 13, Aurora-related kinase 3, Serine/threonine-protein kinase aurora-C, Aurora kinase C, Aurora/IPL1-related kinase 3, AIE2, AIRK3, ARK3, Aurora 3, AURKC, STK13, AIK3, ARK-3, Aurora/IPL1/Eg2 protein 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu20-Gln277 |
| Calculated MW: | 32.32 kDa |
| UniProt: | Q9UQB9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
