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Human BACE1 Antibody (Genentech anti-BACE1) - SDS-PAGE
Key Features

Human BACE1 Antibody (Genentech anti-BACE1) (GXBS02401)

Datasheet MSDS
SKU GXBS02401
Product Type Research Grade Biosimilar
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Clone ID Genentech anti-BACE1
Isotype IgG
$677 - $2,208

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Description

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Human BACE1 Antibody (Genentech anti-BACE1)

Human BACE1 Antibody (Genentech anti-BACE1) is a research-grade biosimilar antibody targeting BACE1. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Beta-secretase 1 (BACE1) is a ~55 kDa protein. Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1.

Product Name:Human BACE1 Antibody (Genentech anti-BACE1)
SKU:GXBS02401
Size:100 µg, 1 mg
Clone:Genentech anti-BACE1
Target:BACE1
Isotype:IgG
Host Species:Human
Reactivity:Human
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:BACE1, Memapsin-2, KIAA1149, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, BACE, Beta-site APP cleaving enzyme 1, Beta-secretase 1, Aspartyl protease 2, ASP2, Membrane-associated aspartic protease 2, BACE1
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P56817
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