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Recombinant BACE1 Monoclonal Antibody (RMEA0069)

Datasheet MSDS
SKU RMEA0069
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110055
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant BACE1 Monoclonal Antibody

The Recombinant BACE1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110055) against BACE1. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Hela and IHC analysis of Human brain. The target is localized to the cell membrane.

Product Name:Recombinant BACE1 Monoclonal Antibody
SKU:RMEA0069
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ASP, ASP2, Aspartyl protease, Aspartyl protease 2, BACE, BACE1, Beta Secretase 1, Beta-secretase, Beta-secretase 1, Beta-site amyloid precursor protein cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme, Beta-site APP cleaving enzyme 1, HSPC, HSPC104, KIAA, KIAA1149, Memapsin, Memapsin 2, Memapsin-2, Membrane-associated aspartic protease, Membrane-associated aspartic protease 2
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human BACE1 protein
Applications:WBIHCIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C110055
Host:Rabbit
Isotype:Rabbit IgG
Target:BACE1
Conjugation:Unconjugated
Observed MW:70 kDa
Calculated MW:56 kDa
Recommended Dilution:IHC 1:100-400; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P56817, P56818, P56819
Purification:Protein A
Concentration:1 mg/mL
Buffer:0.2 µm filtered solution in PBS
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageHuman brain was stained with anti-BACE rabbit antibody
Product ImageVarious whole cell lysates were separated by 4-20% SDS- PAGE, and the membrane was blotted with anti-BACE antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: Hela Predicted band size: 56kDa Observed band size: 70kDa
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