Description
Human BACE1 Recombinant Protein (N-His)
Human BACE1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu46-Thr457, with an N-terminal His tag. Predicted molecular weight: 48.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-secretase 1 (BACE1) is a ~55 kDa protein. Responsible for the proteolytic processing of the amyloid precursor protein (APP). For research use only.
Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1.
| Product Name: | Human BACE1 Recombinant Protein (N-His) |
| SKU: | GXRP01857 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BACE1, Memapsin-2, KIAA1149, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, BACE, Beta-site APP cleaving enzyme 1, Beta-secretase 1, Aspartyl protease 2, ASP2, Membrane-associated aspartic protease 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu46-Thr457 |
| Calculated MW: | 48.21 kDa |
| UniProt: | P56817 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
