Description
Human BLOC1S1 Recombinant Protein (N-His)
Human BLOC1S1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln24-Ser153, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Biogenesis of lysosome-related organelles complex 1 subunit 1 is a ~17 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. For research use only.
In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
| Product Name: | Human BLOC1S1 Recombinant Protein (N-His) |
| SKU: | GXRP13865 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BLOC-1 subunit 1, BLOC1S1, BLOS1, Biogenesis of lysosome-related organelles complex 1 subunit 1, EC:2.3.1.-, GCN5-like protein 1, GCN5L1, Protein RT14, Protein acetyltransferase BLOC1S1, RT14 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln24-Ser153 |
| UniProt: | P78537 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
