Description
Human CBR1 Recombinant Protein (N-His)
Human CBR1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Trp277, with an N-terminal His tag. Predicted molecular weight: 32.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Carbonyl reductase [NADPH] 1 (CBR1) is a ~30 kDa protein. NADPH-dependent reductase with broad substrate specificity. For research use only.
Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.
| Product Name: | Human CBR1 Recombinant Protein (N-His) |
| SKU: | GXRP03391 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CBR1, CRN, Prostaglandin 9-ketoreductase, Carbonyl reductase [NADPH] 1, Short chain dehydrogenase/reductase family 21C member 1, PG-9-KR, Prostaglandin-E(2) 9-reductase, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, CBR, 20-beta-hydroxysteroid dehydrogenase, SDR21C1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Trp277 |
| Calculated MW: | 32.54 kDa |
| UniProt: | P16152 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
