Description

APC Anti-Human CD14 Antibody [M5E2]

The Human CD14 Monoclonal Antibody (APC Conjugated, M5E2, AG2081) offered by AssayGenie is a cutting-edge tool designed for precise research applications involving the CD14 protein. CD14 is a crucial cell surface receptor involved in innate immunity and the recognition of bacterial lipopolysaccharide (LPS), playing a key role in initiating immune responses.This monoclonal antibody, conjugated with allophycocyanin (APC), is specifically tailored for detecting and analyzing CD14 in human samples. With its high sensitivity and specificity, this antibody is ideal for flow cytometry and immunofluorescence applications, allowing researchers to investigate the expression levels and localization of CD14 in different cell types and tissues.

The CD14 Monoclonal Antibody M5E2 (APC Conjugated) offers researchers a valuable tool for studying immune responses, inflammation, and infectious diseases. Its use can provide insights into the activation and regulation of immune cells, serving as a critical component in immunology research and drug development efforts focused on modulating immune function and combatting infectious agents.

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Product Title:	APC Anti-Human CD14 Antibody [M5E2]
SKU:	AGEL2081
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	M5E2
Synonyms:	Monocyte differentiation antigen CD14;CD14;Myeloid cell-specific leucine-rich glycoprotein;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG2a, κ
Isotype Control:	APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	APC
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P08571
Gene ID:	929
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

APC Anti-Human CD14 Antibody [M5E2] (AGEL2081)

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Description