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PE/GenieFluor 594 Anti-Human CD14 Antibody [M5E2] (AGEL3156)

Datasheet MSDS
SKU AGEL3156
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone M5E2
Conjugation PE/AF594
$116 - $545

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/GenieFluor 594 Anti-Human CD14 Antibody [M5E2]

The PE GenieFluor 594 Anti-Human CD14 Antibody (M5E2) offered by Assay Genie is a premium-grade monoclonal antibody designed for precise detection and analysis of the CD14 protein on human cells. This antibody, validated for flow cytometry applications, specifically recognizes CD14, a crucial cell surface marker involved in immune response regulation and inflammation.CD14 is a key component of the innate immune system, primarily expressed on monocytes and macrophages, playing a pivotal role in the recognition of bacterial lipopolysaccharides (LPS) and activation of immune responses. The PE GenieFluor 594 Anti-Human CD14 Antibody (M5E2) provides accurate and sensitive detection of CD14 expression, making it an essential tool for immunology and infection research.

By utilizing this antibody, researchers can gain valuable insights into the function and expression of CD14 in various cell types, aiding in the study of infectious diseases, inflammatory conditions, and immune system dysregulation. Its high specificity and reliability ensure consistent and reproducible results, empowering scientists in their quest to unravel the complexities of the immune system and develop novel therapeutic interventions.

Product Title:PE/GenieFluor 594 Anti-Human CD14 Antibody [M5E2]
SKU:AGEL3156
Size:20 Tests, 100 Tests, 200 Tests
Clone No:M5E2
Synonyms:Monocyte differentiation antigen CD14;CD14;Myeloid cell-specific leucine-rich glycoprotein;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08571
Gene ID:929
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
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