Description
Human CD140b/PDGFRB Recombinant Protein (N-His)
Human CD140b/PDGFRB Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu33-Phe530, with an N-terminal His tag. Predicted molecular weight: 58.42 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Platelet-derived growth factor receptor beta (CD140b/PDGFRB) is a ~123 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. For research use only.
Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli.
| Product Name: | Human CD140b/PDGFRB Recombinant Protein (N-His) |
| SKU: | GXRP03371 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Beta-type platelet-derived growth factor receptor, Beta platelet-derived growth factor receptor, CD140b, Platelet-derived growth factor receptor 1, PDGFRB, PDGF-R-beta, Platelet-derived growth factor receptor beta, CD140 antigen-like family member B, PDGFR-1, PDGFR1, PDGFR-beta, PDGFR |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu33-Phe530 |
| Calculated MW: | 58.42 kDa |
| UniProt: | P09619 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
