The Human CD147 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, HIM6) is a cutting-edge tool for research on CD147, a cell surface glycoprotein known for its diverse roles in cellular functions. This monoclonal antibody, conjugated with PERCP-Cyanine5.5, is specifically designed to target CD147 in human samples, offering a reliable method for its detection and analysis in various experimental settings.CD147, also known as Basigin or EMMPRIN, is a multifunctional protein implicated in various physiological and pathological processes, including cell adhesion, migration, and proliferation. It is particularly noteworthy for its involvement in cancer progression, inflammation, and neurodegenerative disorders.
The HIM6 monoclonal antibody provides researchers with a precise tool to study the expression and localization of CD147 in different cell types, thereby aiding investigations in fields such as oncology, immunology, and neurobiology.By utilizing this advanced antibody, researchers can delve deeper into the molecular mechanisms underlying CD147's functions, paving the way for novel insights into disease pathogenesis and potential therapeutic targets. Its high specificity, validated performance, and compatibility with flow cytometry and other analytical techniques make it an indispensable asset for elucidating the intricate roles of CD147 in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.
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