Description
Human CD167b/DDR2 Recombinant Protein (C-His)
Human CD167b/DDR2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Arg399, with a C-terminal His tag. Predicted molecular weight: 46.02 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Discoidin domain-containing receptor 2 (CD167b/DDR2) is a ~96 kDa protein. Tyrosine kinase involved in the regulation of tissues remodeling. For research use only.
It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion.
| Product Name: | Human CD167b/DDR2 Recombinant Protein (C-His) |
| SKU: | GXRP03482 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Discoidin domain-containing receptor 2, Discoidin domain receptor 2, Tyrosine-protein kinase TYRO10, TKT, TYRO10, CD167b, Discoidin domain-containing receptor tyrosine kinase 2, Receptor protein-tyrosine kinase TKT, DDR2, Neurotrophic tyrosine kinase, receptor-related 3, NTRKR3, CD167 antigen-like family member B |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Arg399 |
| Calculated MW: | 46.02 kDa |
| UniProt: | Q16832 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
