Description
Human CD243/ABCB1 Recombinant Protein (N-GST)
Human CD243/ABCB1 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Phe394-Val672, with an N-terminal GST tag. Predicted molecular weight: 57.72 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent translocase ABCB1 (CD243) is a ~141 kDa protein. Translocates drugs and phospholipids across the membrane. For research use only.
Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
| Product Name: | Human CD243/ABCB1 Recombinant Protein (N-GST) |
| SKU: | GXRP00702 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Phe394-Val672 |
| Calculated MW: | 57.72 kDa |
| UniProt: | P08183 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
