Description
Human CD280/MRC2 Recombinant Protein (N-His)
Human CD280/MRC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro41-Lys505, with an N-terminal His tag. Predicted molecular weight: 55.24 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. C-type mannose receptor 2 (CD280/MRC2) is a ~166 kDa protein. May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. For research use only.
Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover.
| Product Name: | Human CD280/MRC2 Recombinant Protein (N-His) |
| SKU: | GXRP03511 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Urokinase receptor-associated protein, MRC2, CD280, Endocytic receptor 180, KIAA0709, C-type lectin domain family 13 member E, CLEC13E, UPARAP, ENDO180, UPAR-associated protein, C-type mannose receptor 2, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro41-Lys505 |
| Calculated MW: | 55.24 kDa |
| UniProt: | Q9UBG0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
