Description
Human CD2AP Recombinant Protein (N-His)
Human CD2AP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr149-Glu429, with an N-terminal His tag. Predicted molecular weight: 33.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CD2-associated protein (CD2AP) is a ~71 kDa protein. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. For research use only.
In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.
| Product Name: | Human CD2AP Recombinant Protein (N-His) |
| SKU: | GXRP03145 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr149-Glu429 |
| Calculated MW: | 33.01 kDa |
| UniProt: | Q9Y5K6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
