APC Anti-Human CD47 Antibody [CC2C6D4] (AGEL0253)
- SKU:
- AGEL0253
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- CC2C6D4
- Conjugation:
- APC
- Applications:
- FC
![APC Anti-Human CD47 Antibody [CC2C6D4] (AGEL0253)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/20156/605586/apc-anti-human-cd47-antibody-cc2c6d4-agel0253__66930.1707495312.jpg?c=2&imbypass=on "APC Anti-Human CD47 Antibody [CC2C6D4] (AGEL0253)")
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Description
| Product Title: | APC Anti-Human CD47 Antibody [CC2C6D4] |
| SKU: | AGEL0253 |
| Size: | 20 Tests, 100 Tests, 200 Tests |
| Clone No: | CC2C6D4 |
| Synonyms: | Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP; |
| Host Species: | Mouse |
| Reactivity: | Human |
| Application: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | APC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Form: | Liquid |
| Conjugation: | APC |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Spectrum: |  |
| Swissprot: | Q08722 |
| Gene ID: | 961 |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Background: | CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes. |