Human CD70 (MDX-1411) Antibody is a research-grade biosimilar monoclonal antibody. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.
Product Name:
Human CD70 (MDX-1411) Antibody
SKU:
GXBS01132
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
MDX-1411
Target:
CD27 ligand
Isotype:
IgG
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
MDX-1411, MDX1411, MDX1411
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
![APC Anti-Human CD70 Antibody [113-16] (AGEL4775)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/270846/691242/apc-anti-human-cd70-antibody-113-16-agel4775__00929.1774502365.jpg?c=2 "APC Anti-Human CD70 Antibody [113-16] (AGEL4775)")
