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Human CD75/ST6GAL1 Recombinant Protein (C-His)
Key Features

Human CD75/ST6GAL1 Recombinant Protein (C-His) (GXRP03797)

SKU GXRP03797
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human CD75/ST6GAL1 Recombinant Protein (C-His)

Human CD75/ST6GAL1 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Glu44-Cys406, with a C-terminal His tag. Predicted molecular weight: 44.41 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-galactoside alpha-2,6-sialyltransferase 1 (CD75/ST6GAL1) is a ~46 kDa protein. Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. For research use only.

In B lymphocytes, generates neuraminidase-sensitive lymphocyte cell-surface differentiation antigens, such as CDw75, HB-6 and CD76. Sialylates complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs confering anti-inflammatory effector functions. Preferentially monosialylates the alpha(1->3) mannose antenna of Fc glycoforms with subsequent disialylation occurring at a much slower rate.

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