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Human CD85h/LILRA2 Recombinant Protein (C-His)
Key Features

Human CD85h/LILRA2 Recombinant Protein (C-His) (GXRP03869)

SKU GXRP03869
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human CD85h/LILRA2 Recombinant Protein (C-His)

Human CD85h/LILRA2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Asn449, with a C-terminal His tag. Predicted molecular weight: 50.34 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85h/LILRA2) is a ~52 kDa protein. Part of the innate immune responses against microbial infection. For research use only.

Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils.

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