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Human CDC16 Recombinant Protein (N-His)
Key Features

Human CDC16 Recombinant Protein (N-His) (GXRP02149)

SKU GXRP02149
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human CDC16 Recombinant Protein (N-His)

Human CDC16 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser152, with an N-terminal His tag. Predicted molecular weight: 20.18 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cell division cycle protein 16 homolog (CDC16) is a ~71 kDa protein. Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. For research use only.

The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.

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