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Human CDH23 Recombinant Protein (N-His)
Key Features

Human CDH23 Recombinant Protein (N-His) (GXRP03272)

SKU GXRP03272
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CDH23 Recombinant Protein (N-His)

Human CDH23 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning His34-Phe236, with an N-terminal His tag. Predicted molecular weight: 24.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cadherin-23 (CDH23) is a ~369 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. For research use only.

They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

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