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Human CEP164 Recombinant Protein (N-His)
Key Features

Human CEP164 Recombinant Protein (N-His) (GXRP13467)

SKU GXRP13467
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human CEP164 Recombinant Protein (N-His)

Human CEP164 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser106, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Centrosomal protein of 164 kDa is a ~164 kDa protein. Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. For research use only.

Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.

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