Description
Human CHD4 Recombinant Protein (C-His)
Human CHD4 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Gln1912, with a C-terminal His tag. Predicted molecular weight: 218.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in 20 mM Tris-HCl pH 8.0, 100 mM NaCl, 1 mM EDTA, 4%trehalose, 1% mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. For research use only.
Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.
| Product Name: | Human CHD4 Recombinant Protein (C-His) |
| SKU: | GXRP08475 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CHD4, Mi2-beta, Chromodomain-helicase-DNA-binding protein 4, CHD-4, Mi-2 autoantigen 218 kDa protein, ATP-dependent helicase CHD4 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Gln1912 |
| Calculated MW: | 218.98 kDa |
| UniProt: | Q14839 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in 20 mM Tris-HCl pH 8.0, 100 mM NaCl, 1 mM EDTA, 4%trehalose, 1% mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
