Description
Human CIRBP Recombinant Protein (N-His)
Human CIRBP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu172, with an N-terminal His tag. Predicted molecular weight: 20.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cold-inducible RNA-binding protein (CIRBP) is a ~18 kDa protein. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. For research use only.
Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor.
| Product Name: | Human CIRBP Recombinant Protein (N-His) |
| SKU: | GXRP02245 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CIRBP, A18 hnRNP, CIRP, Glycine-rich RNA-binding protein CIRP, A18HNRNP, Cold-inducible RNA-binding protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Glu172 |
| Calculated MW: | 20.81 kDa |
| UniProt: | Q14011 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
