Description
Human CLEC1B Recombinant Protein (N-His)
Human CLEC1B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val56-Pro229, with an N-terminal His tag. Predicted molecular weight: 22.99 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. C-type lectin domain family 1 member B (CLEC1B) is a ~26 kDa protein. C-type lectin-like receptor that serves as a platelet receptor for the lymphatic endothelial marker PDPN. For research use only.
Plays an essential role in blood/lymphatic vessel separation and thrombus formation through homophilic association. Acts as a negative regulator of lymphatic endothelial cell behavior by inhibiting proliferation, migration, and tube formation. Upon ligand binding, triggers a signaling cascade via sequential activation of SRC and SYK tyrosine kinases, leading to activation of PLCG2. Through this pathway, mediates platelet adhesion, aggregation, and secretion in response to PDPN-expressing cells.
| Product Name: | Human CLEC1B Recombinant Protein (N-His) |
| SKU: | GXRP02986 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CLEC1B, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC2, CLEC-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val56-Pro229 |
| Calculated MW: | 22.99 kDa |
| UniProt: | Q9P126 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
