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Human CLIC4 Recombinant Protein (N-His)
Key Features

Human CLIC4 Recombinant Protein (N-His) (GXRP03158)

SKU GXRP03158
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human CLIC4 Recombinant Protein (N-His)

Human CLIC4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys253, with an N-terminal His tag. Predicted molecular weight: 30.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Chloride intracellular channel protein 4 (CLIC4) is a ~28 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. For research use only.

Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

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