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Human COLEC12 Recombinant Protein (N-His)
Key Features

Human COLEC12 Recombinant Protein (N-His) (GXRP09540)

SKU GXRP09540
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human COLEC12 Recombinant Protein (N-His)

Human COLEC12 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu603-Leu742, with an N-terminal His tag. Predicted molecular weight: 18.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Collectin-12 is a ~81 kDa protein. Scavenger receptor that displays several functions associated with host defense. For research use only.

Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Also binds to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR).

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