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Human CREB1 Recombinant Protein (N-His)
Key Features

Human CREB1 Recombinant Protein (N-His) (GXRP01035)

SKU GXRP01035
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CREB1 Recombinant Protein (N-His)

Human CREB1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys122-Asp327, with an N-terminal His tag. Predicted molecular weight: 24.55 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclic AMP-responsive element-binding protein 1 (CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. For research use only.

Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling.

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