Description
Human CRTC3 Recombinant Protein (N-GST)
Human CRTC3 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Met1-Phe103, with an N-terminal GST tag. Predicted molecular weight: 38.5 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CREB-regulated transcription coactivator 3 (CRTC3) is a ~66 kDa protein. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. For research use only.
Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.
| Product Name: | Human CRTC3 Recombinant Protein (N-GST) |
| SKU: | GXRP02465 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CRTC3, Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC3, TORC-3, CREB-regulated transcription coactivator 3 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Met1-Phe103 |
| Calculated MW: | 38.5 kDa |
| UniProt: | Q6UUV7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
