Description
Human CTDSPL Recombinant Protein (N-His)
Human CTDSPL Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro13-Val236, with an N-terminal His tag. Predicted molecular weight: 27.39 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CTD small phosphatase-like protein (CTDSPL) is a ~31 kDa protein. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. For research use only.
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
| Product Name: | Human CTDSPL Recombinant Protein (N-His) |
| SKU: | GXRP03349 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | hYA22, CTD small phosphatase-like protein, YA22, NIFL, NLI-interacting factor 1, RBSP3, SCP3, Small CTD phosphatase 3, CTDSP-like, Nuclear LIM interactor-interacting factor 1, Protein YA22, NIF-like protein, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, C3orf8, NIF1, CTDSPL, Small C-terminal domain phosphatase 3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro13-Val236 |
| Calculated MW: | 27.39 kDa |
| UniProt: | O15194 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
