Description
Human CTPS1 Recombinant Protein (N-His)
Human CTPS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys557, with an N-terminal His tag. Predicted molecular weight: 65.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CTP synthase 1 is a ~66 kDa protein. CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. For research use only.
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. CTPS1 CTP synthase activity plays a crucial role in the proliferation of activated lymphocytes and immunity; additional CTP being required to meet increased demand for DNA, RNA and lipid membrane biosynthesis in proliferating lymphocytes. In addition to CTP synthase activity, also acts as a protein deamidase that catalyzes the side chain deamidation of specific asparagine residues of proteins to aspartate. Acts as a negative regulator of innate immunity by mediating deamidation of 'Asn-85' of IRF3, preventing IRF3 from binding DNA.
| Product Name: | Human CTPS1 Recombinant Protein (N-His) |
| SKU: | GXRP10763 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CTP synthase 1, CTP synthetase 1, CTPS, CTPS1, EC:6.3.4.2, UTP--ammonia ligase 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys557 |
| Calculated MW: | 65.12 kDa |
| UniProt: | P17812 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
