Description
Human CTPS2 Recombinant Protein (N-His)
Human CTPS2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys297, with an N-terminal His tag. Predicted molecular weight: 35.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CTP synthase 2 (CTPS2) is a ~65 kDa protein. CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. For research use only.
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. 1. van Kuilenburg, AB. et al. (2000) Biochimica et biophysica acta 1492, 548-52. PMID: 10899599 2. Han, GS. et al. (2005) The Journal of biological chemistry 280, 38328-36. PMID: 16179339 3. Lynch, EM. et al. (2020) Nature structural & molecular biology 27, 42-48. PMID: 31873303 4. Lynch, EM. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34583994
| Product Name: | Human CTPS2 Recombinant Protein (N-His) |
| SKU: | GXRP05513 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CTPS2, CTP synthetase 2, UTP--ammonia ligase 2, CTP synthase 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys297 |
| Calculated MW: | 35.43 kDa |
| UniProt: | Q9NRF8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |