Description
Human CYP2B6 Recombinant Protein (N-His)
Human CYP2B6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly41-Arg491, with an N-terminal His tag. Predicted molecular weight: 54.11 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cytochrome P450 2B6 is a ~56 kDa protein. A cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids. For research use only.
Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of arachidonoylethanolamide (anandamide) to 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acid ethanolamides (EpETrE-EAs), potentially modulating endocannabinoid system signaling. Hydroxylates steroid hormones, including testosterone at C-16 and estrogens at C-2. Plays a role in the oxidative metabolism of xenobiotics, including plant lipids and drugs.
| Product Name: | Human CYP2B6 Recombinant Protein (N-His) |
| SKU: | GXRP11288 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 1,4-cineole 2-exo-monooxygenase, CYP2B6, CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1, EC:1.14.13.- |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly41-Arg491 |
| Calculated MW: | 54.11 kDa |
| UniProt: | P20813 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
