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Human CYP2E1 Recombinant Protein (N-His)
Key Features

Human CYP2E1 Recombinant Protein (N-His) (GXRP05208)

SKU GXRP05208
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human CYP2E1 Recombinant Protein (N-His)

Human CYP2E1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu32-Ser493, with an N-terminal His tag. Predicted molecular weight: 55.67 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cytochrome P450 2E1 (CYP2E1) is a ~56 kDa protein. A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. For research use only.

Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable).

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