Description
Human PTGER3 Recombinant Protein (N-His)
Human PTGER3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn217-Gln359, with an N-terminal His tag. Predicted molecular weight: 18.36 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Prostaglandin E2 receptor EP3 subtype (PTGER3) is a ~43 kDa protein. Receptor for prostaglandin E2 (PGE2). For research use only.
The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium. Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration.
| Product Name: | Human PTGER3 Recombinant Protein (N-His) |
| SKU: | GXRP01605 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PTGER3, PGE2-R, PGE2 receptor EP3 subtype, Prostanoid EP3 receptor, Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn217-Gln359 |
| Calculated MW: | 18.36 kDa |
| UniProt: | P43115 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
